Evidence Synthesis: Nursing

Use this guide as a resource for your evidence synthesis research.

Research question frameworks

The point of a framework is to help you identify, articulate, and define the component parts of your research question.

Not all frameworks are suited to all questions. If you're asking a question that doesn't have a clinical, intervention- or experimentation-based approach, trying to fit your research question into a PICO framework will not be helpful. There are many well-established frameworks that are intended for different research approaches. Think about the elements of your research as you browse through the various options below.

Frameworks

Use the grid to identify frameworks that might fit your research parameters. Explore frameworks of interest further by selecting its tab.

Email us if there is a framework that should be included with this list.

  Clinical Quantitative Qualitative Mixed Methods

PICO

yes yes    
PEO     yes  
SPIDER     yes yes
SPICE    

yes

 

Explore the list of references below for an in-depth examination of these frameworks.

PICO

Patient / Population

Intervention

Comparison

Outcome

 

Used for: clinical research questions favouring interventions and experimental research

 

Example Article with PICO question

Alanazi, A. A., & Nicholson, N. (2023). The Use of Simulation in Audiology Education: A Systematic Review. American Journal of Audiology, 32(3), 640–656. https://doi.org/10.1044/2023_AJA-23-00054

PEO

Population

Exposure

Outcome

 

Used for: qualitative research questions favouring correlations or looking into experiences

 

Example Article with PEO question

Ortolan, A., Cozzi, G., Lorenzin, M., Galozzi, P., Doria, A., & Ramonda, R. (2021). The Genetic Contribution to Drug Response in Spondyloarthritis: A Systematic Literature Review. Frontiers in genetics, 12, 703911. https://doi.org/10.3389/fgene.2021.703911

SPIDER

Sample

Phenomenon of Interest

Design

Evaluation

Research type

 

Used for: qualitative or mixed methods research that focuses on samples of populations rather than patients or populations

 

Example Article with SPIDER Question

Althumairy R. I. (2022). Exploring the Quality of Life for Saudi Patients Utilizing Dental Healthcare Services: A Systematic Review. Journal of multidisciplinary healthcare, 15, 309–315. https://doi.org/10.2147/JMDH.S344963

SPICE

Setting

Perspective

Intervention/exposure/interest

Comparison

Evaluation

 

Used for: qualitative research focussed on evaluating the outcomes of an intervention or project

 

Example Article with SPICE question

Phelan, S., Lin, F., Mitchell, M., & Chaboyer, W. (2018). Implementing early mobilisation in the intensive care unit: An integrative review. International Journal of Nursing Studies, 77, 91–105. https://doi.org/10.1016/j.ijnurstu.2017.09.019

What if none of the frameworks fit my question?

There is nothing wrong with having a question that doesn't fit an established framework!

It's worth evaluating and editing your question before deciding that you need to invent your own framework. Perhaps you're interpreting a framework element in one way, but it could be understood in a way that allows it to match your question.

More important than fitting a pre-defined framework, though, is ensuring that your question is clearly articulated and well-defined.